Mechanisms Underlying Sesamolin-Induced Attenuation of Vascular Dysfunction in Rats With Streptozotocin-Induced Diabetes
نویسندگان
چکیده
Article history: Received: 20 Nov 2010 Revised: 27 Jan 2011 Accepted: 09 Feb 2011
منابع مشابه
Soybean feeding improves vascular dysfunction and atte-nuates oxidative stress in streptozotocin-diabetic rats
Background and Objective: In this research, the effect of chronic dietary soybean aqueous extract on aortic reactivity of streptozotocin (STZ)-diabetic rats was investigated. Materials and Methods: STZ-diabetic rats were treated with soybean aqueous extract for two months after diabetes induction. Contractile reactivity to KCl and phenylephrine (PE) and relaxation response to acetylcholine (ACh...
متن کاملEndothelium-dependent Effect of Sesame Seed Feeding on Vascular Reactivity of Streptozotocin-diabetic Rats: Underlying Mechanisms
Cardiovascular disorders continue to constitute major causes of morbidity and mortality in diabetic patients. In this study, the effect of chronic administration of sesame (Sesamum indicum L) seed feeding was studied on aortic reactivity of streptozotocin (STZ)-diabetic rats. Male diabetic rats received sesame seed-mixed food at weight ratios of 3% and 6% for 7 weeks, one week after diabetes in...
متن کاملProtective effect of curcumin in fructose-induced metabolic syndrome and in streptozotocin-induced diabetes in rats
Objective: The aim of this study was to investigate the effect of pre-treatment with curcumin on metabolic changes induced by two different pathophysiological mechanisms in rats (fructose diet and streptozotocin (STZ)-induced diabetes mellitus). Materials and Methods: Five groups with 10 rats per group were investigated: control group (healthy rats), fructose diet groups without any pre-treatme...
متن کاملAqueous extract of Berberis integerrima root improves renal dysfunction in streptozotocin induced diabetic rats
Objective: Barberry root extract contains various alkaloids that are considered as antioxidants. Beneficial effect of aqueous extract of Berberis integerrima root (AEBIR) was evaluated for renal function in diabetic rats induced by STZ. Material and Methods: Diabetes was induced by i.p. injection of streptozotocin (65 mg/kg bw) to rats, after 15 h of fasting. Diabetic rats were randomly grouped...
متن کاملSesame effects on testicular damage in streptozotocin-induced diabetes rats
Objective(s): Reproductive dysfunction is a consequence of diabetes. Diabetes is associated with changes in testicular tissue. Sesame oil contains large amounts of polyunsaturated fatty acids and lignin with antioxidant activity, vitamin E, and monounsaturated fatty acid (MUFA). The present study investigated the effects of sesame on testis histology and male reproductive parameters in streptoz...
متن کامل